Pierce a capsule of vitamin E and squeeze the oil on to a cotton bud or tissue, then dab at the cold sore. Or, better still, soak a bigger piece of cotton wool well in the oil and hold it over the sore for 10 – 15 minutes twice a day. This brings topical relief and can clear up the sore which can be pretty persistent sometimes within a couple of days. The main problem of clearing the sore will give you a complete relief for it and would enable you to get rid of it very soon. So follow all the preventive measures and get rid of it as quick as possible.